Table of Contents: Italian Sausage Meatloaf
Italian Sausage Meatloaf
There’s something undeniably comforting about a slice of warm, juicy meatloaf—especially when it’s packed with the bold flavors of Italian sausage, melty mozzarella, and rich marinara sauce. This Italian Sausage Meatloaf is a delicious twist on the traditional recipe, bringing a hearty, restaurant-quality dish to your family dinner table. Perfect for busy weeknights, Sunday suppers, or holiday gatherings, this recipe delivers savory, moist, and flavorful results every time. Whether you’re a meatloaf enthusiast or looking for hearty meatloaf dinner ideas, this dish is sure to become a new favorite.
Introduction: Italian Sausage Meatloaf
Meatloaf is a timeless comfort food, but when you add Italian sausage into the mix, you elevate it to a whole new level. This Italian Sausage Meatloaf combines lean ground beef with spiced Italian sausage, creating a rich, juicy texture that’s bursting with flavor. The addition of Parmesan cheese, Italian breadcrumbs, and gooey mozzarella makes every bite irresistible, while a generous layer of marinara sauce ties everything together in a deliciously saucy finish.
This recipe is perfect for those nights when you crave easy comfort food for family dinners but still want something special. It’s also a fantastic dish for entertaining—whether it’s a cozy family gathering or a holiday feast. Plus, leftovers (if there are any!) make for excellent sandwiches the next day.
If you love Italian sausage recipes and are looking for baked meatloaf inspiration, this dish checks all the boxes. It’s simple to prepare, packed with flavor, and guaranteed to satisfy even the pickiest eaters.
Alternate Names & Variations
This dish goes by a few different names, so if you’re searching for similar recipes, try looking for:
– Italian-Style Meatloaf
– Cheesy Sausage Meatloaf
– Meatloaf with Italian Sausage and Mozzarella
For variations, you could swap the marinara sauce for pesto or Alfredo sauce, or add sautéed mushrooms for extra depth. If you’re looking for more hearty meatloaf dinner ideas, consider trying a bacon-wrapped version or adding sun-dried tomatoes for a Mediterranean twist.
Ingredients: Italian Sausage Meatloaf

Here’s everything you’ll need to make this flavor-packed Italian Sausage Meatloaf:
- – 1 Tablespoon oil (for sautéing)
- – 1 small onion, finely diced
- – 1 bell pepper, finely diced
- – 1 lb. lean ground beef (85/15 or 90/10 works best)
- – 1 lb. Italian sausage (mild or spicy, depending on preference)
- – 1 teaspoon Worcestershire sauce (for umami depth)
- – ½ teaspoon garlic powder
- – 1 teaspoon dried oregano
- – 2 large eggs (to bind the mixture)
- – 1 cup Italian breadcrumbs (for texture)
- – ½ cup grated Parmesan cheese
- – 8 oz. shredded mozzarella cheese, divided (half inside, half on top)
- – 2 cups marinara sauce, divided (1 cup mixed in, 1 cup for topping)
Step-by-Step Instructions
1. Preheat & Prep: Preheat your oven to 375°F (190°C). Lightly grease a loaf pan or line a baking sheet with parchment paper.
2. Sauté Veggies: Heat 1 Tbsp oil in a skillet over medium heat. Add onion and bell pepper, cooking until softened (about 5 minutes). Let cool slightly.
3. Mix the Meatloaf: In a large bowl, combine ground beef, Italian sausage, Worcestershire sauce, garlic powder, oregano, eggs, breadcrumbs, Parmesan, ½ the mozzarella, and 1 cup marinara sauce. Mix gently (overmixing can make it dense).
4. Shape & Bake: Transfer the mixture to the loaf pan or shape into a free-form loaf on the baking sheet. Bake for 45 minutes.
5. Add Toppings: Remove from oven, spread the remaining 1 cup marinara sauce on top, and sprinkle with the rest of the mozzarella. Return to the oven for 10-15 minutes, or until the cheese is bubbly and golden.
6. Rest & Serve: Let the meatloaf rest for 10 minutes before slicing. This keeps it juicy!
Chef’s Tip: For extra moisture, add ¼ cup milk or beef broth to the meat mixture.
Recipe Card Block (Quick Reference)
Prep Time: 15 mins | Cook Time: 55 mins | Total Time: 1 hr 10 mins | Servings: 6 | Calories: ~450 per serving
Why This Recipe Works & Expert Tips
– Flavor Boost: The Italian sausage adds a bold, herby kick that regular meatloaf lacks.
– Cheesy Goodness: The mozzarella inside and on top makes every bite extra indulgent.
– Perfect Texture: The breadcrumbs and eggs keep the meatloaf tender, not dry.
– Easy Comfort Food: This is a one-pan meal that’s simple yet impressive.
Pro Tip: Use a meat thermometer—the internal temperature should reach 160°F (71°C) for safe eating.
Storage, Freezing, and Reheating Tips
– Storage: Keep leftovers in an airtight container for 3-4 days in the fridge.
– Freezing: Slice and freeze for up to 3 months. Thaw overnight before reheating.
– Reheating: Warm in the oven at 350°F (175°C) for 15-20 minutes or microwave until hot.
People Also Ask: Italian Sausage Meatloaf

What makes Italian sausage meatloaf different from regular meatloaf?
Italian sausage meatloaf has a richer, spicier flavor thanks to the fennel, garlic, and herbs in the sausage. Unlike traditional meatloaf, which relies on ketchup or brown sugar glaze, this version uses marinara and mozzarella for an Italian-inspired twist.
How do you keep Italian sausage meatloaf moist and flavorful?
The key is not overmixing the meat and using eggs, breadcrumbs, and marinara to retain moisture. Adding cheese inside the loaf also helps prevent dryness. Letting it rest before slicing locks in juices.
Can you substitute Italian sausage in a classic meatloaf recipe?
Absolutely! Swap half the ground beef for Italian sausage to add depth. Adjust seasoning as needed since sausage is already well-spiced.
What temperature and time should Italian sausage meatloaf be cooked to?
Bake at 375°F (190°C) for 55-60 minutes, or until the internal temperature reaches 160°F (71°C).
Conclusion: Italian Sausage Meatloaf
This Italian Sausage Meatloaf is a hearty, flavorful upgrade to the classic dish. Whether you’re serving it for a weeknight dinner or a special occasion, it’s guaranteed to impress. Try it tonight and let us know how it turns out—share your results on Pinterest or Facebook!
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Italian Sausage Meatloaf
- Total Time: 1 hour 15 minutes
- Yield: 6 servings 1x
Description
A hearty and flavorful twist on classic meatloaf, combining Italian sausage, ground beef, herbs, and gooey mozzarella, topped with rich marinara.
Ingredients
- 1 Tablespoon oil
- 1 small onion, finely chopped
- 1 bell pepper, finely chopped
- 1 lb. lean ground beef
- 1 lb. Italian sausage
- 1 teaspoon Worcestershire sauce
- ½ teaspoon garlic powder
- 1 teaspoon oregano
- 2 large eggs
- 1 cup Italian bread crumbs
- ½ cup Parmesan cheese
- 8 oz. shredded mozzarella cheese, divided
- 2 cups marinara sauce, divided
Instructions
- Preheat the oven to 375°F (190°C).
- In a skillet, heat oil over medium heat and sauté chopped onion and bell pepper until softened. Let cool slightly.
- In a large bowl, combine ground beef, Italian sausage, sautéed vegetables, Worcestershire sauce, garlic powder, oregano, eggs, bread crumbs, Parmesan, and half of the mozzarella.
- Mix until well combined and shape into a loaf on a lined baking sheet or place in a loaf pan.
- Spread 1 cup of marinara sauce over the top.
- Bake for 45-55 minutes or until cooked through.
- Top with remaining marinara sauce and mozzarella cheese. Return to oven for 5-10 minutes until cheese is melted and bubbly.
- Let rest for 10 minutes before slicing and serving.
Notes
For extra flavor, use spicy Italian sausage. Letting the meatloaf rest helps keep it juicy when sliced.
- Prep Time: 15 minutes
- Cook Time: 60 minutes
- Category: Dinner
- Method: Baked
- Cuisine: Italian-American
Nutrition
- Serving Size: 1 slice
- Calories: 520
- Sugar: 5g
- Sodium: 950mg
- Fat: 35g
- Saturated Fat: 14g
- Unsaturated Fat: 18g
- Trans Fat: 0g
- Carbohydrates: 15g
- Fiber: 2g
- Protein: 35g
- Cholesterol: 130mg
Keywords: meatloaf, Italian sausage, ground beef, marinara, cheesy dinner