Best Southern Meatloaf Recipe: Comfort Food Made Easy!

Table of Contents: Southern Meatloaf

Southern Meatloaf

There’s nothing quite like a hearty slice of Southern Meatloaf—juicy, flavorful, and smothered in tangy BBQ sauce. This homestyle meatloaf is the ultimate comfort food, perfect for Sunday suppers, holiday gatherings, or a simple weeknight meal that brings everyone to the table.

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Introduction: Southern Meatloaf Recipe

When it comes to Southern comfort food, few dishes hit the spot like a well-made Southern meatloaf. Unlike traditional versions, this recipe packs bold flavors with a mix of ground beef and pork, smoky spices, and a sweet-and-savory BBQ glaze.

This homestyle meatloaf is a nostalgic favorite, evoking memories of family dinners and Southern hospitality. Whether you’re serving it for a cozy weeknight meal or a holiday feast, this recipe delivers tender, juicy results every time.

The secret? A blend of Vidalia onions, green bell peppers, and Cajun seasoning for depth, plus a sticky BBQ sauce topping that caramelizes beautifully in the oven. It’s the kind of dish that keeps everyone coming back for seconds!

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Alternate Names & Variations

This Southern meatloaf recipe goes by a few other names, depending on where you’re from:

– BBQ Meatloaf (thanks to the tangy glaze)
– Old-Fashioned Meatloaf (for a classic touch)
– Smoky Southern Meatloaf (due to the paprika and Cajun seasoning)

Looking for a twist? Try swapping the BBQ sauce for ketchup glaze or adding a sprinkle of sharp cheddar cheese inside the loaf.

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Ingredients: Southern Meatloaf Recipe

Here’s what you’ll need for this comfort food meatloaf:

• – 2 tablespoons vegetable oil (for sautéing)
• – 1 cup Vidalia onion, finely chopped (for sweetness)
• – ½ cup green bell pepper, finely chopped (for freshness)
• – 4 cloves garlic, minced (for bold flavor)
• – 1 cup store-bought dry breadcrumbs (plain or Italian-style)
• – ½ cup whole milk (keeps the loaf moist)
• – 1 (4-oz) jar diced pimientos, drained (adds color & mild tang)
• – ¼ cup + ¾ cup BBQ sauce, divided (for inside and glaze)
• – 1 tablespoon Worcestershire sauce (for umami depth)
• – 2 large eggs, lightly beaten (binder for the loaf)
• – 1 pound 80/20 ground beef (for richness)
• – 1 pound ground pork (for tenderness)
• – 2 teaspoons smoked paprika (for a smoky kick)
• – 1¼ teaspoons Cajun seasoning (for Southern flair)
• – ½ teaspoon salt (to taste)
• – ¼ teaspoon black pepper (for balance)

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Step-by-Step Instructions

1. Sauté the Aromatics

Heat vegetable oil in a skillet over medium heat. Add onions, bell peppers, and garlic, cooking until softened (about 5 minutes). Let cool slightly.

2. Soak the Breadcrumbs

In a large bowl, combine breadcrumbs and milk, letting them soak for 2–3 minutes.

3. Mix the Meatloaf

Add the sautéed veggies, pimientos, ¼ cup BBQ sauce, Worcestershire sauce, eggs, beef, pork, paprika, Cajun seasoning, salt, and pepper to the breadcrumb mixture. Gently mix until just combined—overmixing makes the loaf tough!

4. Shape & Bake

Transfer the mixture to a greased loaf pan or shape into a free-form loaf on a baking sheet. Spread the remaining ¾ cup BBQ sauce on top.

Bake at 375°F (190°C) for 50–60 minutes, or until the internal temperature reaches 160°F (71°C).

5. Rest & Serve

Let the meatloaf rest for 10 minutes before slicing. This keeps it juicy!

Chef’s Tip: For extra caramelization, broil the loaf for 2–3 minutes at the end.

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Recipe Card (Quick Reference)

| Prep Time | Cook Time | Total Time | Servings | Calories |
| 15 mins | 60 mins | 75 mins | 6–8 | ~350/slice |

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Why This Recipe Works & Expert Tips

– Perfect Texture: The combo of beef and pork ensures a tender, juicy loaf.
– Flavor Boost: Smoked paprika and Cajun seasoning add a Southern kick.
– BBQ Glaze: The sticky BBQ topping caramelizes for a sweet-savory finish.

Pro Tip: For a gluten-free version, swap breadcrumbs for crushed pork rinds or gluten-free oats.

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Storage, Freezing & Reheating Tips

– Fridge: Store leftovers in an airtight container for 3–4 days.
– Freezer: Wrap slices tightly in foil and freeze for up to 3 months.
– Reheating: Warm in a 350°F oven or microwave with a splash of broth to retain moisture.

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People Also Ask: Southern Meatloaf Recipe

What Makes Southern Meatloaf Different from Traditional Meatloaf?

Southern meatloaf often includes Cajun spices, BBQ sauce, and a mix of beef and pork, giving it a richer, smokier flavor than traditional versions.

What Type of Breadcrumbs Are Best for Southern-Style Meatloaf?

Plain dry breadcrumbs work well, but Italian-seasoned crumbs add extra flavor. For a Southern touch, some cooks use cornbread crumbs.

Can You Make Southern Meatloaf with Barbecue Sauce?

Absolutely! BBQ sauce is a key ingredient—both mixed inside and brushed on top for a sticky glaze.

What Side Dishes Go Best with Southern Meatloaf?

Classic pairings include mashed potatoes, collard greens, mac and cheese, or buttered cornbread.

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Conclusion: Southern Meatloaf Recipe

This Southern meatloaf recipe is the ultimate comfort food—tender, flavorful, and smothered in BBQ goodness. Whether it’s a weeknight dinner or a holiday feast, this dish always satisfies.

Try it tonight and share your results in the comments!

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Happy cooking! 🍽️

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